MRSI Acquisition
- Siemens 7 T scanner
- MP2RAGE sequence (1 mm isotropic resolution, TR/TE/flip angle 1/ flip angle 2: 6000 ms/2.47 ms/40/50)
- J-refocused spectroscopic imaging sequence (Pan et al., 2010) (TE/TR = 2 ×17/1500 ms)
- An 8 × 2 1 H transceiver array using 8 independent RF channels was used to acquire data
- High order shimming was used to optimize homogeneity of the B0 magnetic field.
- The 2D CSI oblique axial slice
- Conventional rectangular phase encoding of 24 × 24 over a FOV of 216 × 216 mm
- 10 mm thick, 0.9 ×0.9 ×1.0 cm nominal resolution
- acquisition slice position guided by MRSI Slice Positioning tool (QPASA)
Analysis
- metabolite concentrations derived with LC Model from ROIs placed by MRSI ROI Coordinate placement tool
- concentration adjusted with GAM modeling
- output stored in 7T Data: merge_7t.csv