Brain Mechanisms R01 (7T)

• RA main "packet" esp. topsheet and overview
• Magnetic Resonance
  • 7T Resting State fMRI
  • Scan sheet docx - sequence acquisition duration and order
• Magnetic Resonance Spectroscopy Imaging
  • MRSI Acquisition
  • LC Model
  • MRSI in HC @ 7T
  • PFC ROI Placement
  • 7T MR Quality Check

• Electroencephalogram
  • EEG at Loeffler
  • EEG Preprocessing Pipeline for 7T/BrainMechR01
  • Spectral Event Pipeline
  • Fitting Oscillations and 1/f (FOOOF)
  • Signal to Noise Ratio (SNR)

• 7T Sample Information

• 7T Data: merge_7t.csv - combined data across measures as a large csv - row per visit year
• Merge 7T EEG - combined data across all EEG measures per channel as a large csv
• sop - how tasks are administered and data is collected

Resulting Publications

1. Age-related differences in transient gamma band activity during working memory maintenance through adolescence
2. Aperiodic EEG and 7T MRSI evidence for maturation of E/I balance supporting the development of working memory through adolescence
3. Puberty contributes to adolescent development of fronto-striatal functional connectivity supporting inhibitory control
4. Variation in Striatal Dopamine-Related Neurophysiology Supports Age-Related Differences in GABA and Glutamate Through Human Adolescence
5. Development of frontal GABA and glutamate supports excitation/inhibition balance from adolescence into adulthood
6. Impact of stress on excitatory and inhibitory markers of adolescent cognitive critical period plasticity
7. Pubertal development underlies optimization of inhibitory control through specialization of ventrolateral prefrontal cortex