MRSI Acquisition
Siemens 7 T scanner
MP2RAGE sequence (1 mm isotropic resolution, TR/TE/flip angle 1/ flip angle 2: 6000 ms/2.47 ms/40/50)
J-refocused spectroscopic imaging sequence (Pan et al., 2010) (TE/TR = 2 ×17/1500 ms)
An 8 × 2 1 H transceiver array using 8 independent RF channels was used to acquire data
High order shimming was used to optimize homogeneity of the B0 magnetic field.
The 2D CSI oblique axial slice
Conventional rectangular phase encoding of 24 × 24 over a FOV of 216 × 216 mm
10 mm thick, 0.9 ×0.9 ×1.0 cm nominal resolution
acquisition slice position guided by
MRSI Slice Positioning tool (QPASA)
Analysis
metabolite concentrations derived with
LC Model
from ROIs placed by
MRSI ROI Coordinate placement tool
concentration adjusted with
GAM
modeling
output stored in
7T Data: merge_7t.csv