===== MRSI Acquisition ===== * Siemens 7 T scanner * MP2RAGE sequence (1 mm isotropic resolution, TR/TE/flip angle 1/ flip angle 2: 6000 ms/2.47 ms/40/50) * J-refocused spectroscopic imaging sequence (Pan et al., 2010) (TE/TR = 2 ×17/1500 ms) * An 8 × 2 1 H transceiver array using 8 independent RF channels was used to acquire data * High order shimming was used to optimize homogeneity of the B0 magnetic field. * The 2D CSI oblique axial slice * Conventional rectangular phase encoding of 24 × 24 over a FOV of 216 × 216 mm * 10 mm thick, 0.9 ×0.9 ×1.0 cm nominal resolution * acquisition slice position guided by [[:tools:QPASAslicewarp]] ==== Analysis ==== * metabolite concentrations derived with [[:tools:lcmodel]] from ROIs placed by [[:tools:mrsicoordmover]] * concentration adjusted with [[:tools:gam]] modeling * output stored in [[:grants:7t:data]]